Population genetic studies of the pancreatic amylase (AMY2, E.C. 3.2.1.1) in Bulgaria.
نویسندگان
چکیده
The pancreatic amylase (AMY2, E.C. 3.2.1.1) polymorphism has been studied in 2346 individuals from south-central and south-eastern Bulgaria. The allele frequencies have been determined as AMY2*1 = 0.9520 and AMY2*2 = 0.0480. The neighbor joining tree of seven subpopulations revealed only small genetic distances. Compared with other populations, the Bulgarian sample clustered with samples from Romania, Hungary, Germany and Switzerland, with larger distances to Albania, Greece and Macedonia.
منابع مشابه
PURIFICATIO N OF ALPHA-AMYLASE FROM BACILLUS SUBTILlS LINE # 1024 WITH ATCC 465
Alpha-amylase E.C.3.2.1.1. (1,4 glucan, 4 glucanohydrolase) can be obtained from salivary glands, pancreas and microorganisms such as Pseudomonas and Asperigllus, as well as muscles and ovarian tubes.1.2 Alpha-amylase from Bacillus Subtilis #1024(A TCC 465)* was purified with a highest degree of purity in our laboratory (31.59 U/mg). The extracellular alpha-amylase was subjected to differe...
متن کاملRelationship between salivary/pancreatic amylase and body mass index: a systems biology approach
BACKGROUND Salivary (AMY1) and pancreatic (AMY2) amylases hydrolyze starch. Copy number of AMY1A (encoding AMY1) was reported to be higher in populations with a high-starch diet and reduced in obese people. These results based on quantitative PCR have been challenged recently. We aimed to re-assess the relationship between amylase and adiposity using a systems biology approach. METHODS We ass...
متن کاملDNA sequence evolution of the amylase multigene family in Drosophila pseudoobscura.
The alpha-Amylase locus in Drosophila pseudoobscura is a multigene family of one, two or three copies on the third chromosome. The nucleotide sequences of the three Amylase genes from a single chromosome of D. pseudoobscura are presented. The three Amylase genes differ at about 0.5% of their nucleotides. Each gene has a putative intron of 71 (Amy1) or 81 (Amy2 and Amy3) bp. In contrast, Drosoph...
متن کاملTABLE II FINDINGS FROM EIGHT PATIENTS WITH KNOWN PANCREATIC DISEASE ( GROuP 2 ) AND CASES OF
The quantitation of isoenzymes in body fluids has obvious applications in the diagnosis of disease. a-Amylase (E.C. 3.2.1.1.), of molecular weight 50,000, also occurs in multiple molecular forms. This heterogeneity was initially discovered in animals and later extended to man. The evidence has been principally electrophoretic (N0rby, 1964; Muus and Vnenchak, 1964: Berk, Searcey, Hayashi, and Uj...
متن کاملThe level and origin of amylase (EC 3.2.1.1) in the digestive tract of chicks receiving trypsin inhibitors in their diet.
1. Amylase (EC 3.2.1.1) activity found in the intestinal tract of chicks posterior to the stomach is of endogenous origin, as amylase in the food is inactivated by the low pH in the stomachs. 2. Ingestion of raw soya-bean diet (RSD) or of heated soya-bean diet (HSD) supplemented with trypsin inhibitors induced higher amylase activites in the lower part of the small intestine and caecum as compa...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Collegium antropologicum
دوره 28 Suppl 2 شماره
صفحات -
تاریخ انتشار 2004